The benefits of the therapeutic use of marijuana are well known. Although prohibition makes it difficult to conduct scientific studies on medical marijuana, there are more and more that corroborate its usefulness for different pathologies.
The benefits of the therapeutic use of marijuana are well known. Although prohibition makes it difficult to carry out scientific studies on medical marijuana, there are more and more that corroborate its usefulness for different pathologies.
Furthermore, although they cannot be used as the results of a scientific study, we have the experiences and testimonies of many patients who claim to have been able to alleviate the effects of their illnesses thanks to Cannabis.
Medical marijuana: a brief history
Cannabis is recognized as one of the first plants cultivated and used by man. In fact there is evidence of its use in China 4,000 years before Christ.
During the 19th century it was introduced into Western medicine by the French psychiatrist Jacques-Joseph Moreau and the Irish doctor William B. O’Shaughnessy.
During the 20th century, the prohibition of the use of Cannabis, both recreational and medicinal, is materialized. The persecution of Cannabis begins in the USA with the publication in 1937 of the Marijuana Tax Act and extends throughout the planet with the 1961 UN Single Convention on Narcotic Drugs.
Medical marijuana: the cannabinoids
It is the cannabinoids, substances present in the resin of Cannabis, that provide the medicinal effects of marijuana. Possible therapeutic benefits of terpenes and flavonoids (odorous and taste substances) are also currently being studied.
Of the cannabinoids, THC was the most studied, as it is responsible for the psychoactive effects of marijuana. Many therapeutic applications for CBD are also known today.
For this reason many of the most sought-after strains of marijuana currently for medical use are known to have a 1:1 ratio. These varieties produce plants that contain similar percentages of THC as CBD.
Synthetic cannabinoids, such as Nabilone (Cesamet) in the case of THC, have been manufactured. But it seems that for many diseases, it is the combination of all cannabinoids in the plant that produces the medicinal effect.
According to information disclosed by Canna Research Laboratories, the differences between the characteristics of the main cannabinoids present in marijuana
- The first cannabinoid produced by the plant
- Precursor of CBD and TCH.
- Predominantly soporific.
- Cannabidiol (CBD)
It is created by degradation of the CBG.
- Precursor of THC.
- Slightly psychoactive.
- Suppresses feelings of fear and panic.
- Reduces the effect of THC
- It’s created by CBD degradation.
- CBN precursor.
- Main psychoactive component of marijuana.
- Its effects can be: relaxants, stimulants or hallucinogens and raise the pulse
- It is created by degradation of THC.
- Present in poorly preserved plants or cut too late.
- Slightly psychoactive.
When cannabinoids are in the plant it has an acid form, a bud does not contain THC but THCA, which is much less powerful.
The difference is that THCA has a tail composed of a carbon molecule, which must be lost to become THC. This is known as decarboxylation. The easiest way is to heat it up to a certain level. This is easily done with cannabis that’s smoked, steamed or cooked.
If, for example, you want to consume the buds directly, without burning or cooking them, it is recommended that you leave them in a bain-marie for two hours to decarboxylate them, transform the THCA into THC and thus achieve the same effect using a smaller amount of marijuana.